Vahl [Oleaceae; Forsythiae Fructus] (255g), Lonicera japonica Thunb. DerSimonian, R., and Laird, N. (1986). A Working List of All Plant Species. Use Overdosage Contraindications Special Precautions Adverse Reactions Storage MIMS Class ATC . For drowsiness of nervous system damage, sample size (p = 0.500), year of publication (p = 0.157), and treatment of the control group (p = 0.599) were not linked with heterogeneity. COVID-19 pandemic has caused a serious threat to public health and become the greatest challenge facing the world. Six studies reported the adverse reactions of abnormal white blood cells and reticuloendothelial system. 12, 640782. doi:10.3389/fphar.2021.640782. Guo H., Zhang Q.H., Yang J., Gong J.N., Zhao Y.S., Zhou X.P. Meta-Analysis of Efficacy of Oseltamivir and Substitution Therapy for Anti- H1n1 Infection. Salvi R., Patankar P. Emerging pharmacotherapies for COVID-19. 17 (13), 6264. There was no statistically significant difference in the incidence of adverse reactions during treatment of common pneumonia between the LHQW group and the conventional drug group (RR = 0.99, 95% CI = 0.791.24, p = 0.927). Are there any known contraindications? J. Ethnopharmacol. ADVERSE REACTION Uncertainty. The term adverse reaction represents any undesired and unintended response that occurs with normal drug use (Gallelli et al., 2002). Lianhua Qingwen is a commonly used Chinese patent medicine to treat viral infection. LHQW is now officially recorded in Chinese Pharmacopeia (2015 Edition) and has been used to treat viral influenza for more than one decade, including in the fight against SARS in 20022003 in China [17]. Pharmacokinetics-based identification of pseudoaldosterogenic compounds Fig. (2021). Beggs test and Eggers test detected no visible publication bias for data from pooled studies and disease evaluation. [Cruciferae; Isatudus Radix] (255g), Dryopteris crassirhizoma Nakai [Polypodiaceae; Dryopteris Crassirhizomatis Rhizoma] (255g), Houttuynia cordata Thunb. After 7 days of treatment, the main TCM syndrome scores (fever, fatigue, cough, dry throat, chest tightness), C-reactive protein and procalcitonin levels in the LHQW group were significantly lower, and the white blood cell and lymphocyte counts were obviously higher than those in abidor group [44]. New Progress in Study on Mechanism of Lianhua Qingwen Capsules for Identification of a pharmacological biomarker for the bioassay-based quality control of a thirteen-component TCM formula (Lianhua Qingwen) used in treating influenza A virus (H1N1) infection. There was no statistically significant difference in the incidence of adverse reactions during treatment of other diseases between the LHQW group and the conventional drug group (RR = 0.95, 95% CI = 0.651.39, p = 0.780). 66 (6), 771777. In conclusion, this review has summarized the benefits of LHQW for treating virus infection, especially its anti-SARS-CoV-2 role as an alternative candidate and complementary strategy.